The Molecular Basis Of Sex And Differentiation

Autor: Milton H. Saier
Publisher: Springer Science & Business Media
ISBN: 1461252601
File Size: 23,75 MB
Format: PDF, Kindle
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Man's mind stretched to a new idea never goes back to its original dimensions Oliver Wendell Holmes Our current understanding of sex and biological differentiation results from the application of three principal experimental approaches to these subjects: those of the physiologist, the biochemist, and the geneticist. These three approaches are illustrated by the materials presented in the chapters of this volume. Chapters 1-5 emphasize conceptualization of developmental processes, describing systems principally from the standpoint of the physiologist. Structures and functions are defined with only occasional reference to specific molecular details. Chapters 6- 10 present the views of the biochemist, attempting to describe functions influ encing or regulating cellular behavior at the molecular level. And Chapters 11- 14 illustrate the approaches of the modem-day geneticist in his attempts to gain a detailed understanding of processes controlling gene expression. While it is possible to delineate these three major sections, each emphasizing a distinct experimental approach, it must be realized that the yield of knowledge increases exponentially with the number of experimental approaches available to the investigator. Information resulting from the application of each of these approaches must converge to give the same answers for anyone biological phenomenon in anyone experimental system. Further, if we can learn of details regarding a particular process by applying different experimental approaches, our postulates concerning the underlying molecular mechanisms are likely to be more accurate. But biological systems are not unrelated.

Molecular Biology Of The Cell

Autor: Bruce Alberts
Publisher: Garland Science
ISBN: 1317563743
File Size: 55,73 MB
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As the amount of information in biology expands dramatically, it becomes increasingly important for textbooks to distill the vast amount of scientific knowledge into concise principles and enduring concepts.As with previous editions, Molecular Biology of the Cell, Sixth Edition accomplishes this goal with clear writing and beautiful illustrations. The Sixth Edition has been extensively revised and updated with the latest research in the field of cell biology, and it provides an exceptional framework for teaching and learning. The entire illustration program has been greatly enhanced.Protein structures better illustrate structure–function relationships, icons are simpler and more consistent within and between chapters, and micrographs have been refreshed and updated with newer, clearer, or better images. As a new feature, each chapter now contains intriguing openended questions highlighting “What We Don’t Know,” introducing students to challenging areas of future research. Updated end-of-chapter problems reflect new research discussed in the text, and these problems have been expanded to all chapters by adding questions on developmental biology, tissues and stem cells, pathogens, and the immune system.


Autor: Denise R. Ferrier
Publisher: Lippincott Williams & Wilkins
ISBN: 1451175620
File Size: 44,36 MB
Format: PDF, ePub
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Lippincott's Illustrated Reviews: Biochemistry is the long-established first-and best resource for the essentials of biochemistry. Students rely on this text to help them quicklyreview, assimilate, and integrate large amounts of critical and complex information. For more than two decades, faculty and students have praisedLIR Biochemistry's matchless illustrations that make concepts come to life.NEW! extensive revisions and updated content integrative and chapter-based cases new and updated figures new questions bonus online chapter on Blood Clotting Plus all the hallmark features you count on from Lippincott's Illustrated Reviews: Outline format – perfect for both concise review and foundational learning Annotated, full-color illustrations – visually explain complex biochemical processes Chapter overviews and summaries – reinforce your study time Clinical boxes – take students quickly from the classroom to the patient, associating key concepts with real-world scenarios More than 200 review questions in the book FREE with purchase! A comprehensive online exam featuring 500+ practice questions, plus fully searchable eBook

Cellular And Molecular Immunology E Book

Autor: Abul K. Abbas
Publisher: Elsevier Health Sciences
ISBN: 0323286453
File Size: 78,71 MB
Format: PDF, Mobi
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Popular for its highly visual, straightforward approach, Cellular and Molecular Immunology delivers an accessible yet thorough understanding of this active and fast-changing field. Drs. Abul K. Abbas, Andrew H. Lichtman, and Shiv Pillai present key updates in this new edition to cover the latest developments in antigen receptors and signal transduction in immune cells, mucosal and skin immunity, cytokines, leukocyte-endothelial interaction, and more. With additional online features, this is an ideal resource for medical, graduate and undergraduate students of immunology who need a clear, introductory text for immunology courses. Consult this title on your favorite e-reader, conduct rapid searches, and adjust font sizes for optimal readability. Develop a thorough, clinically relevant understanding of immunology through a clear overview of immunology with a distinct focus on the management of human disease. Visualize immunologic processes more effectively. Meticulously developed and updated illustrations, 3-dimensional art, and all-new animations provide a detailed, visual description of the key immunologic and molecular processes. Grasp the details of experimental observations that form the basis for the science of immunology at the molecular, cellular, and whole-organism levels and draw the appropriate conclusions. Find information more quickly and easily through an organized chapter structure and a more logical flow of material. Glean all essential, up-to-date, need-to-know information about immunology and molecular biology through extensive updates that cover cytokines, innate immunity, leukocyte-endothelial interactions, signaling, costimulation, and more. Benefit from numerous new figures and tables that facilitate easier retention of the material; quick summaries of each chapter; and nearly 400 illustrations that clarify key concepts.

Mol Cell Biology Molecular Cell Biolo Paper

Autor: Darnell
Publisher: Springer
ISBN: 9780716714484
File Size: 46,56 MB
Format: PDF
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Revised and updated edition (1st was 1986) of a rigorous undergraduate text that integrates molecular biology with biochemistry, cell biology, and genetics and applies the unifying insight to such problems as development, immunology, and cancer. Annotation copyrighted by Book News, Inc., Portland, OR

Gene Control

Autor: David Latchman
Publisher: Garland Science
ISBN: 1136844201
File Size: 21,55 MB
Format: PDF, Docs
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Gene Control offers a current description of how gene expression is controlled in eukaryotes, reviewing and summarizing the extensive primary literature into an easily accessible format. Gene Control is a comprehensively restructured and expanded edition of Latchman’s Gene Regulation: A Eukaryotic Perspective, Fifth Edition. The first part of the book deals with the fundamental processes of gene control at the levels of chromatin structure, transcription, and post-transcriptional processes. Three pairs of chapters deal with each of these aspects, first describing the basic process itself, followed by the manner in which it is involved in controlling gene expression. The second part of the book deals with the role of gene control in specific biological processes. Certain chapters deal with the importance of gene control in cellular signaling processes and for normal development of the embryo. Another chapter discusses the key roles played by gene-regulatory processes in the specification of differentiated cell types such as muscle cells and neurons. The final chapters discuss the consequences of errors in gene control; the relationship between gene misregulation and human diseases, especially cancer; and potential therapies designed specifically to target particular levels of gene control. Gene Control will be of value to students in biological sciences, as well as to scientists and clinicians interested in how genes are regulated in health and disease.